2021
Nuno M Luis and Frank Schnorrer
Mechanobiology of muscle and myofibril morphogenesis.
Cells Dev. 2021 Dec 1:203760. doi: 10.1016/j.cdev.2021.203760. PMID: 34863916
Arno Meiler, Fabio Marchiano, Margaux Haering, Manuela Weitkunat, Frank Schnorrer, Bianca H Habermann
AnnoMiner is a new web-tool to integrate epigenetics, transcription factor occupancy and transcriptomics data to predict transcriptional regulators. Sci Rep. 2021 Jul 29;11(1):15463. doi: 10.1038/s41598-021-94805-1. PMID: 34326396
Clara Sidor, Frank Schnorrer
Mechanobiology: Forging a strong matrix at tendons.
Curr Biol. 2021 Apr 12;31(7):R347-R350. doi: 10.1016/j.cub.2021.01.092. PMID: 33848491
Jerome Avellaneda, Clement Rodier, Fabrice Daian, Nicolas Brouilly, Thomas Rival, Nuno Miguel Luis, Frank Schnorrer
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle.
Nat Commun. 2021 Apr 7;12(1):2091. doi: 10.1038/s41467-021-22058-7. PMID: 33828099
Aynur Kaya-Çopur, Fabio Marchiano, Marco Y Hein, Daniel Alpern, Julie Russeil, Nuno Miguel Luis, Matthias Mann, Bart Deplancke, Bianca H Habermann, Frank Schnorrer
The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression.
Elife. 2021 Jan 6;10:e63726. doi: 10.7554/eLife.63726. PMID: 33404503
2020
Marica Catinozzi, Moushami Mallik, Marie Frickenhaus, Marije Been, Céline Sijlmans, Divita Kulshrestha, Ioannis Alexopoulos, Manuela Weitkunat, Frank Schnorrer, Erik Storkebaum
The Drosophila FUS ortholog cabeza promotes adult founder myoblast selection by Xrp1-dependent regulation of FGF signaling.
PLoS Genet. 2020 Apr 17;16(4):e1008731. doi: 10.1371/journal.pgen.1008731. PMID: 32302304
2019
Julia Sauerwald, Wilko Backer, Till Matzat, Frank Schnorrer, Stefan Luschnig
Matrix metalloproteinase 1 modulates invasive behavior of tracheal branches during entry into Drosophila flight muscles.
Elife. 2019 Oct 2;8. pii: e48857. doi: 10.7554/eLife.48857. PMID: 31577228
Sandra B Lemke, Thomas Weidemann, Anna-Lena Cost, Carsten Grashoff, Frank Schnorrer
A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo.
PLoS Biol. 2019 Mar 27;17(3):e3000057. doi: 10.1371/journal.pbio.3000057
PMID: 30917109
Aynur Kaya-Çopur and Frank Schnorrer
RNA Interference Screening for Genes Regulating Drosophila Muscle Morphogenesis.
Methods Mol Biol. 2019;1889:331-348. doi: 10.1007/978-1-4939-8897-6_20
PMID: 30367424
2018
Sandra B Lemke, Thomas Weidemann, Anna-Lena Cost, Carsten Grashoff, Frank Schnorrer
A small proportion of Talin molecules transmit forces to achieve muscle attachment in vivo
bioRXiv. 2018 Oct 17; doi: https://doi.org/10.1101/446336
Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Xu Zhang, Sandra B Lemke, Adrien Bonnard, Erich Brunner, Giovanni Cardone, Konrad Basler, Bianca H Habermann, Frank Schnorrer
A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle
Elife. 2018 May 30;7. pii: e34058. doi: 10.7554/eLife.34058. [Epub ahead of print]. PMID: 29846170
Kinjal Dasbiswas, Shiqiong Hu, Frank Schnorrer, Samuel A. Safran, Alexander D. Bershadsky
Ordering of myosin II filaments driven by mechanical forces: experiments and theory
Philos Trans R Soc Lond B Biol Sci. 2018 May 26;373(1747). pii: 20170114. doi: 10.1098/rstb.2017.0114
Olivier Loison, Manuela Weitkunat, Aynur Kaya-Çopur, Camila Nascimento Alves, Till Matzat, Maria L. Spletter, Stefan Luschnig, Sophie Brasselet, Pierre-François Lenne, Frank Schnorrer
Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation
PLoS Biol. 2018 Apr 27;16(4):e2004718. doi: 10.1371/journal.pbio.2004718. [Epub ahead of print] PMID: 29702642
Sandra B Lemke, Frank Schnorrer
In Vivo Imaging of Muscle-tendon Morphogenesis in Drosophila Pupae
J Vis Exp. 2018 Feb 6;(132). doi: 10.3791/57312. PMID: 29443094
2017
Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Xu Zhang, Sandra B Lemke, Erich Brunner, Giovanni Cardone, Konrad Basler, Bianca H Habermann, Frank Schnorrer
Systematic transcriptomics reveals a biphasic mode of sarcomere morphogenesis in flight muscles regulated by Spalt
bioRXiv. 2017 Dec 5;
Kanca O, Bellen HJ, Schnorrer F.
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila.
Genetics. 2017 Oct;207(2):389-412. doi: 10.1534/genetics.117.199968.
Weitkunat M, Brasse M, Bausch A, Schnorrer F.
Mechanical tension and spontaneous muscle twitching precede the formation of cross-striated muscle in vivo.
Development. 2017 Apr 1;144(7):1261-1272. doi: 10.1242/dev.140723. Epub 2017 Feb 7.
PMID: 28174246
Zhang X, Schnorrer F.
AIDing-targeted protein degradation in Drosophila.
FEBS J. 2017 Apr;284(8):1178-1181. doi: 10.1111/febs.14054. Epub 2017 Apr 5.
PMID: 28382696
2016
Lemke SB, Schnorrer F.
Mechanical forces during muscle development.
Mech Dev. 2016 Nov 29. pii: S0925-4773(16)30104-6. doi: 10.1016/j.mod.2016.11.003. Review.
PMID: 27913119
Kaya-Çopur A, Schnorrer F.
A Guide to Genome-Wide In Vivo RNAi Applications in Drosophila.
Methods Mol Biol. 2016;1478:117-143. PMID: 27730578
Sarov M, Barz C, Jambor H, Hein MY, Schmied C, Suchold D, Stender B, Janosch S, K J VV, Krishnan RT, Krishnamoorthy A, Ferreira IR, Ejsmont RK, Finkl K, Hasse S, Kämpfer P, Plewka N, Vinis E, Schloissnig S, Knust E, Hartenstein V, Mann M, Ramaswami M, VijayRaghavan K, Tomancak P, Schnorrer F.
A genome-wide resource for the analysis of protein localisation in Drosophila.
Elife. 2016 Feb 20;5:e12068. doi: 10.7554/eLife.12068. PMID: 26896675
2015
Ordan E, Brankatschk M, Dickson B, Schnorrer F, Volk T.
Slit cleavage is essential for producing an active, stable, non-diffusible short-range signal that guides muscle migration.
Development. 2015 Apr 15;142(8):1431-6. doi: 10.1242/dev.119131. PMID: 25813540
Spletter ML, Barz C, Yeroslaviz A, Schönbauer C, Ferreira IR, Sarov M, Gerlach D, Stark A, Habermann BH, Schnorrer F.
The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle.
EMBO Rep. 2015 Feb;16(2):178-91. doi: 10.15252/embr.201439791. PMID: 25532219
2014
Zhang X, Koolhaas WH, Schnorrer F.
A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila.
G3 (Bethesda). 2014 Oct 15;4(12):2409-18. doi: 10.1534/g3.114.013979. PMID: 25324299
Zhang X, Ferreira IR, Schnorrer F.
A simple TALEN-based protocol for efficient genome-editing in Drosophila.
Methods. 2014 Aug 15;69(1):32-7. doi: 10.1016/j.ymeth.2014.03.020. PMID: 24680697
Weitkunat M, Schnorrer F.
A guide to study Drosophila muscle biology.
Methods. 2014 Jun 15;68(1):2-14. doi: 10.1016/j.ymeth.2014.02.037. Review. PMID: 24625467
Weitkunat M, Kaya-Çopur A, Grill SW, Schnorrer F.
Tension and force-resistant attachment are essential for myofibrillogenesis in Drosophila flight muscle.
Curr Biol. 2014 Mar 31;24(7):705-16. doi: 10.1016/j.cub.2014.02.032. PMID: 24631244
Klein P, Müller-Rischart AK, Motori E, Schönbauer C, Schnorrer F, Winklhofer KF, Klein R.
Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants.
EMBO J. 2014 Feb 18;33(4):341-55. doi: 10.1002/embj.201284290. Epub 2014 Jan 28. Erratum in: EMBO J. 2014 Apr 1:33(7):779. PMID: 24473149
Spletter ML, Schnorrer F.
Transcriptional regulation and alternative splicing cooperate in muscle fiber-type specification in flies and mammals.
Exp Cell Res. 2014 Feb 1;321(1):90-8. doi: 10.1016/j.yexcr.2013.10.007. Epub 2013 Oct 19. Review. PMID: 24145055
2011
Schönbauer C, Distler J, Jährling N, Radolf M, Dodt HU, Frasch M, Schnorrer F.
Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects.
Nature. 2011 Nov 16;479(7373):406-9. doi: 10.1038/nature10559. PMID: 22094701
Hatan M, Shinder V, Israeli D, Schnorrer F, Volk T.
The Drosophila blood brain barrier is maintained by GPCR-dependent dynamic actin structures.
J Cell Biol. 2011 Jan 24;192(2):307-19. doi: 10.1083/jcb.201007095. Epub 2011 Jan 17. PMID: 21242289
2010
Schnorrer F, Schönbauer C, Langer CC, Dietzl G, Novatchkova M, Schernhuber K, Fellner M, Azaryan A, Radolf M, Stark A, Keleman K, Dickson BJ.
Systematic genetic analysis of muscle morphogenesis and function in Drosophila.
Nature. 2010 Mar 11;464(7286):287-91. doi: 10.1038/nature08799. PMID: 20220848
Jährling N, Becker K, Schönbauer C, Schnorrer F, Dodt HU.
Three-dimensional reconstruction and segmentation of intact Drosophila by ultramicroscopy.
Front Syst Neurosci. 2010 Feb 8;4:1. doi: 10.3389/neuro.06.001.2010. eCollection 2010. PMID: 20204156
Langer CC, Ejsmont RK, Schönbauer C, Schnorrer F, Tomancak P.
In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura.
PLoS One. 2010 Jan 28;5(1):e8928. doi: 10.1371/journal.pone.0008928. PMID: 20126626
2008
Chen D, Ahlford A, Schnorrer F, Kalchhauser I, Fellner M, Viràgh E, Kiss I, Syvänen AC, Dickson BJ.
High-resolution, high-throughput SNP mapping in Drosophila melanogaster.
Nat Methods. 2008 Apr;5(4):323-9. doi: 10.1038/nmeth.1191. Epub 2008 Mar 9. PMID: 18327265
Becker K, Jährling N, Kramer ER, Schnorrer F, Dodt HU.
Ultramicroscopy: 3D reconstruction of large microscopical specimens.
J Biophotonics. 2008 Mar;1(1):36-42. doi: 10.1002/jbio.200710011. PMID: 19343633
Schnorrer F, Ahlford A, Chen D, Milani L, Syvänen AC.
Positional cloning by fast-track SNP-mapping in Drosophila melanogaster.
Nat Protoc. 2008;3(11):1751-65. doi: 10.1038/nprot.2008.175. PMID: 18948975
2007
Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, Fellner M, Gasser B, Kinsey K, Oppel S, Scheiblauer S, Couto A, Marra V, Keleman K, Dickson BJ.
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.
Nature. 2007 Jul 12;448(7150):151-6. PMID: 17625558
Schnorrer F, Kalchhauser I, Dickson BJ.
The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila.
Dev Cell. 2007 May;12(5):751-66. PMID: 17488626
2006
Vogt N, Koch I, Schwarz H, Schnorrer F, Nüsslein-Volhard C.
The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline.
Development. 2006 Oct;133(20):3963-72. Epub 2006 Sep 13. PMID: 16971473
2005
Grosshans J, Wenzl C, Herz HM, Bartoszewski S, Schnorrer F, Vogt N, Schwarz H, Müller HA.
RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation.
Development. 2005 Mar;132(5):1009-20. Epub 2005 Feb 2. PMID: 15689371
2004
Schnorrer F, Dickson BJ.
Muscle building; mechanisms of myotube guidance and attachment site selection.
Dev Cell. 2004 Jul;7(1):9-20. Review. PMID: 15239950
Schnorrer F, Dickson BJ.
Axon guidance: morphogens show the way.
Curr Biol. 2004 Jan 6;14(1):R19-21. Review. PMID: 14711429
2002
Schnorrer F, Luschnig S, Koch I, Nüsslein-Volhard C.
Gamma-tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during drosophila oogenesis.
Dev Cell. 2002 Nov;3(5):685-96. PMID: 12431375
2000
Schnorrer F, Bohmann K, Nüsslein-Volhard C.
The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes.
Nat Cell Biol. 2000 Apr;2(4):185-90. PMID: 10783235
1999
Grosshans J, Schnorrer F, Nüsslein-Volhard C.
Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.
Mech Dev. 1999 Mar;81(1-2):127-38. PMID: 10330490
1998
Nayler O, Schnorrer F, Stamm S, Ullrich A.
The cellular localization of the murine serine/arginine-rich protein kinase CLK2 is regulated by serine 141 autophosphorylation.
J Biol Chem. 1998 Dec 18;273(51):34341-8. PMID: 9852100