Publications

2018

Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Xu Zhang, Sandra B Lemke, Adrien Bonnard, Erich Brunner, Giovanni Cardone, Konrad Basler, Bianca H Habermann, Frank Schnorrer
A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle
Elife. 2018 May 30;7. pii: e34058. doi: 10.7554/eLife.34058. [Epub ahead of print]. PMID: 29846170

Kinjal Dasbiswas, Shiqiong Hu, Frank Schnorrer, Samuel A. Safran, Alexander D. Bershadsky
Ordering of myosin II filaments driven by mechanical forces: experiments and theory
Philos Trans R Soc Lond B Biol Sci. 2018 May 26;373(1747). pii: 20170114. doi: 10.1098/rstb.2017.0114

Olivier Loison, Manuela Weitkunat, Aynur Kaya-Çopur, Camila Nascimento Alves, Till Matzat, Maria L. Spletter, Stefan Luschnig, Sophie Brasselet, Pierre-François Lenne, Frank Schnorrer
Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation
PLoS Biol. 2018 Apr 27;16(4):e2004718. doi: 10.1371/journal.pbio.2004718. [Epub ahead of print] PMID: 29702642

Sandra B Lemke, Frank Schnorrer
In Vivo Imaging of Muscle-tendon Morphogenesis in Drosophila Pupae
J Vis Exp. 2018 Feb 6;(132). doi: 10.3791/57312. PMID: 29443094

2017

Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Xu Zhang, Sandra B Lemke, Erich Brunner, Giovanni Cardone, Konrad Basler, Bianca H Habermann, Frank Schnorrer
Systematic transcriptomics reveals a biphasic mode of sarcomere morphogenesis in flight muscles regulated by Spalt
bioRXiv. 2017 Dec 5;

Kanca O, Bellen HJ, Schnorrer F.
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila.
Genetics. 2017 Oct;207(2):389-412. doi: 10.1534/genetics.117.199968.

Weitkunat M, Brasse M, Bausch A, Schnorrer F.
Mechanical tension and spontaneous muscle twitching precede the formation of cross-striated muscle in vivo.
Development. 2017 Apr 1;144(7):1261-1272. doi: 10.1242/dev.140723. Epub 2017 Feb 7.
PMID: 28174246

Zhang X, Schnorrer F.
AIDing-targeted protein degradation in Drosophila.
FEBS J. 2017 Apr;284(8):1178-1181. doi: 10.1111/febs.14054. Epub 2017 Apr 5.
PMID: 28382696

2016

Lemke SB, Schnorrer F.
Mechanical forces during muscle development.
Mech Dev. 2016 Nov 29. pii: S0925-4773(16)30104-6. doi: 10.1016/j.mod.2016.11.003. Review.
PMID: 27913119

Kaya-Çopur A, Schnorrer F.
A Guide to Genome-Wide In Vivo RNAi Applications in Drosophila.
Methods Mol Biol. 2016;1478:117-143. PMID: 27730578

Sarov M, Barz C, Jambor H, Hein MY, Schmied C, Suchold D, Stender B, Janosch S, K J VV, Krishnan RT, Krishnamoorthy A, Ferreira IR, Ejsmont RK, Finkl K, Hasse S, Kämpfer P, Plewka N, Vinis E, Schloissnig S, Knust E, Hartenstein V, Mann M, Ramaswami M, VijayRaghavan K, Tomancak P, Schnorrer F.
A genome-wide resource for the analysis of protein localisation in Drosophila.
Elife. 2016 Feb 20;5:e12068. doi: 10.7554/eLife.12068. PMID: 26896675

2015

Ordan E, Brankatschk M, Dickson B, Schnorrer F, Volk T.
Slit cleavage is essential for producing an active, stable, non-diffusible short-range signal that guides muscle migration.
Development. 2015 Apr 15;142(8):1431-6. doi: 10.1242/dev.119131. PMID: 25813540

Spletter ML, Barz C, Yeroslaviz A, Schönbauer C, Ferreira IR, Sarov M, Gerlach D, Stark A, Habermann BH, Schnorrer F.
The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle.
EMBO Rep. 2015 Feb;16(2):178-91. doi: 10.15252/embr.201439791. PMID: 25532219

2014

Zhang X, Koolhaas WH, Schnorrer F.
A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila.
G3 (Bethesda). 2014 Oct 15;4(12):2409-18. doi: 10.1534/g3.114.013979. PMID: 25324299

Zhang X, Ferreira IR, Schnorrer F.
A simple TALEN-based protocol for efficient genome-editing in Drosophila.
Methods. 2014 Aug 15;69(1):32-7. doi: 10.1016/j.ymeth.2014.03.020. PMID: 24680697

Weitkunat M, Schnorrer F.
A guide to study Drosophila muscle biology.
Methods. 2014 Jun 15;68(1):2-14. doi: 10.1016/j.ymeth.2014.02.037. Review. PMID: 24625467

Weitkunat M, Kaya-Çopur A, Grill SW, Schnorrer F.
Tension and force-resistant attachment are essential for myofibrillogenesis in Drosophila flight muscle.
Curr Biol. 2014 Mar 31;24(7):705-16. doi: 10.1016/j.cub.2014.02.032. PMID: 24631244

Klein P, Müller-Rischart AK, Motori E, Schönbauer C, Schnorrer F, Winklhofer KF, Klein R.
Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants.
EMBO J. 2014 Feb 18;33(4):341-55. doi: 10.1002/embj.201284290. Epub 2014 Jan 28. Erratum in: EMBO J. 2014 Apr 1:33(7):779. PMID: 24473149

Spletter ML, Schnorrer F.
Transcriptional regulation and alternative splicing cooperate in muscle fiber-type specification in flies and mammals.
Exp Cell Res. 2014 Feb 1;321(1):90-8. doi: 10.1016/j.yexcr.2013.10.007. Epub 2013 Oct 19. Review. PMID: 24145055

2011

Schönbauer C, Distler J, Jährling N, Radolf M, Dodt HU, Frasch M, Schnorrer F.
Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects.
Nature. 2011 Nov 16;479(7373):406-9. doi: 10.1038/nature10559. PMID: 22094701

Hatan M, Shinder V, Israeli D, Schnorrer F, Volk T.
The Drosophila blood brain barrier is maintained by GPCR-dependent dynamic actin structures.
J Cell Biol. 2011 Jan 24;192(2):307-19. doi: 10.1083/jcb.201007095. Epub 2011 Jan 17. PMID: 21242289

2010

Schnorrer F, Schönbauer C, Langer CC, Dietzl G, Novatchkova M, Schernhuber K, Fellner M, Azaryan A, Radolf M, Stark A, Keleman K, Dickson BJ.
Systematic genetic analysis of muscle morphogenesis and function in Drosophila.
Nature. 2010 Mar 11;464(7286):287-91. doi: 10.1038/nature08799. PMID: 20220848

Jährling N, Becker K, Schönbauer C, Schnorrer F, Dodt HU.
Three-dimensional reconstruction and segmentation of intact Drosophila by ultramicroscopy.
Front Syst Neurosci. 2010 Feb 8;4:1. doi: 10.3389/neuro.06.001.2010. eCollection 2010. PMID: 20204156

Langer CC, Ejsmont RK, Schönbauer C, Schnorrer F, Tomancak P.
In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura.
PLoS One. 2010 Jan 28;5(1):e8928. doi: 10.1371/journal.pone.0008928. PMID: 20126626

2008

Chen D, Ahlford A, Schnorrer F, Kalchhauser I, Fellner M, Viràgh E, Kiss I, Syvänen AC, Dickson BJ.
High-resolution, high-throughput SNP mapping in Drosophila melanogaster.
Nat Methods. 2008 Apr;5(4):323-9. doi: 10.1038/nmeth.1191. Epub 2008 Mar 9. PMID: 18327265

Becker K, Jährling N, Kramer ER, Schnorrer F, Dodt HU.
Ultramicroscopy: 3D reconstruction of large microscopical specimens.
J Biophotonics. 2008 Mar;1(1):36-42. doi: 10.1002/jbio.200710011. PMID: 19343633

Schnorrer F, Ahlford A, Chen D, Milani L, Syvänen AC.
Positional cloning by fast-track SNP-mapping in Drosophila melanogaster.
Nat Protoc. 2008;3(11):1751-65. doi: 10.1038/nprot.2008.175. PMID: 18948975

2007

Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, Fellner M, Gasser B, Kinsey K, Oppel S, Scheiblauer S, Couto A, Marra V, Keleman K, Dickson BJ.
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.
Nature. 2007 Jul 12;448(7150):151-6. PMID: 17625558

Schnorrer F, Kalchhauser I, Dickson BJ.
The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila.
Dev Cell. 2007 May;12(5):751-66. PMID: 17488626

2006

Vogt N, Koch I, Schwarz H, Schnorrer F, Nüsslein-Volhard C.
The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline.
Development. 2006 Oct;133(20):3963-72. Epub 2006 Sep 13. PMID: 16971473

2005

Grosshans J, Wenzl C, Herz HM, Bartoszewski S, Schnorrer F, Vogt N, Schwarz H, Müller HA.
RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation.
Development. 2005 Mar;132(5):1009-20. Epub 2005 Feb 2. PMID: 15689371

2004

Schnorrer F, Dickson BJ.
Muscle building; mechanisms of myotube guidance and attachment site selection.
Dev Cell. 2004 Jul;7(1):9-20. Review. PMID: 15239950

Schnorrer F, Dickson BJ.
Axon guidance: morphogens show the way.
Curr Biol. 2004 Jan 6;14(1):R19-21. Review. PMID: 14711429

2002

Schnorrer F, Luschnig S, Koch I, Nüsslein-Volhard C.
Gamma-tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during drosophila oogenesis.
Dev Cell. 2002 Nov;3(5):685-96. PMID: 12431375

2000

Schnorrer F, Bohmann K, Nüsslein-Volhard C.
The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes.
Nat Cell Biol. 2000 Apr;2(4):185-90. PMID: 10783235

1999

Grosshans J, Schnorrer F, Nüsslein-Volhard C.
Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.
Mech Dev. 1999 Mar;81(1-2):127-38. PMID: 10330490

1998

Nayler O, Schnorrer F, Stamm S, Ullrich A.
The cellular localization of the murine serine/arginine-rich protein kinase CLK2 is regulated by serine 141 autophosphorylation.
J Biol Chem. 1998 Dec 18;273(51):34341-8. PMID: 9852100