Institut de Biologie du Développement de Marseille & Aix Marseille Université (UMR7288)
qiyan . mao [at] univ-amu.fr
Short Bio
I am a Chinese national. After obtaining my bachelor’s degree from Peking University, I went to the University of Chicago to study classic embryology with Dr. Robert Ho. I was fascinated by how the vertebrate limb skeleton self-organize to generate a complex shape. Wishing to find out how cells interact to drive morphogenesis, I joined Dr. Thomas Lecuit’s group at the IBDM as a postdoc fellow, where I uncovered how cell surface receptors encode mechanical interfaces between distinct fate groups. Now I am a postdoc researcher in Dr. Frank Schnorrer’s group at the IBDM in collaboration with Dr. Olivier Pourquié’s group at Harvard University. Using human iPSC-derived muscle progenitors, I take a synthetic approach to understand cell interactions during muscle morphogenesis in vitro. I dream of reconstructing the musculoskeletal system with the minimal sufficient cell interactions.
Education
2013 | Ph.D. in Developmental Biology, University of Chicago, United States |
2006 | B.S. in Biological Sciences (magna cum laude), Peking University, China |
Research Experience
2023.10-present | Chargée de recherche CNRS |
2019.1-2023.9 | Postdoctoral researcher Aix Marseille Université & Institut de Biologie du Développement de Marseille Advisor: Frank Schnorrer, PhD Research subject: mechanical self-organisation in human iPSC-derived myofibers |
2014.3-2018.4 | Postdoctoral fellow CNRS & Institut de Biologie du Développement de Marseille Advisor: Thomas Lecuit, PhD Research subject: cell surface signaling and cytoskeleton polarity |
2008.9 – 2013.8 | PhD Thesis Committee on Developmental Biology, University of Chicago Advisor: Robert K. Ho, PhD Thesis: Spatial Dynamics and Regulation of the Zebrafish Limb Morphogenetic Field. ProQuest Dissertations & Theses Global. (2013) ISBN 9781303423185. |
Research grants and fellowships
2024-2028 ANR-JCJC, project MECHANOMUS (340 K euros)
2022-2023 AFM-Téléthon postdoc fellowship
2012 Doolittle-Harrison Fellowship, University of Chicago
2011-2013 Chicago Biomedical Consortium Fellowship
2003-2006 Presidential Scholarship for Undergraduate Research, Peking University
2003-2006 Baosteel Education Foundation Scholarship
Students supervised
2025- Romain Giromini, PhD student (co-supervision with Frank Schnorroer)
2024- Laila Boubeker, PhD student (co-supervision with Frank Schnorroer)
2024 Noémie Vergne, M1 internship, Université de Clermont Auvergne
2024 Hanyu Wang, undergraduate thesis, WUT-AMU institute
2021 Swedha Sidharthan, PhD thesis committee member, Aix-Marseille Université
2016-2017 Jules Lavalou, M2 internship, Aix-Marseille Université
2011 Jiajie Xu, PhD rotation student, University of Chicago
2010 Haley Stinnett, PhD rotation student, University of Chicago
2009 Carrie Albertin, PhD rotation student, University of Chicago
Teaching Experience
2022 Chargée d’enseignement vacataire Niveau L1, WUT-AMU
UE : « Génétique Moleculaire Eukaryote » (CM ; 42 HeTD)
2008 Teaching assistant, Niveau L3, University of Chicago
UE : « Cours pratique de biologie du développement » (TP ; 72 h HeTD)
2007 Teaching assistant, Niveau doctorat, University of Chicago
UE : « Analyse génétique des organismes modèles » (TD ; 48 h HeTD)
Publications
Qiyan Mao†*, Achyuth Acharya†, Alejandra Rodriguez-delaRosa, Fabio Marchiano, Benoit Dehapiot, Ziad Al Tanoury, Jyoti Rao, Margarete Diaz-Cuadros, Arian Mansur, Erica Wagner, Claire Chardes, Vandana A Gupta, Pierre-Francois Lenne, Bianca H Habermann, Olivier Pourquié*, Frank Schnorrer*
Tension-driven multi-scale self-organisation in human iPSC-derived muscle fibers
†co-first author, *co-corresponding author
eLife, (2022) Aug 3;11:e76649. doi: 10.7554/eLife.76649
Erin B. Anderson, Qiyan Mao, Robert K. Ho. Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Developmental Biology (2021), accepted
Jules Lavalou*, Qiyan Mao*,†, Stefan Harmansa, Stephen Kerridge, Annemarie C. Lellouch, Jean-Marc Philippe, Stephane Audebert, Luc Camoin, Thomas Lecuit†. Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry. Developmental Cell (2021) doi.org/10.1016/j.devcel.2021.03.030.
* co-first author
† co-corresponding author
This article is featured in: doi.org/10.1016/j.devcel.2021.05.013
Qiyan Mao, Jules Lavalou and Thomas Lecuit.Fat2 and Lar Dance a Pas de Deux during Collective Cell Migration.Developmental Cell. (2017), 40(5):425-426. doi: 10.1016/j.devcel.2017.02.025.
Qiyan Mao and Thomas Lecuit. Evo–Devo: Universal Toll Pass for the Extension Highway?Current Biology (2016), 26 (14): R680-R683. doi: 10.1016/j.cub.2016.05.063
Qiyan Mao and Thomas Lecuit.Mechanochemical interplay drives polarization in cellular and developmental systems.Current Topics in Developmental Biology (2016) 116:633-57. doi: 10.1016/bs.ctdb.2015.11.039
Qiyan Mao, Haley K. Stinnett and Robert K. Ho.Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal.Development (2015) 142: 4329-4339; doi: 10.1242/dev.124750
Qiyan Mao, Stephen L. Johnson, and Robert K. Ho.How to make a new appendage: Invasive dermal skeleton contributes to a novel fin in a zebrafish mutant.Developmental Biology (2009) 331(2):460. doi: 10.1016/j.ydbio.2009.05.278
Hongzheng Dai, Ying Chen, Sidi Chen, Qiyan Mao, David Kennedy, Patrick Landback, Adam Eyre-Walker, Wei Du, and Manyuan Long. The evolution of courtship behaviors through the origination of a new gene in Drosophila
PNAS (2008) 105(21): 7478–7483. doi: 10.1073/pnas.0800693105.
Oral Presentations
- 2021 Marseille Medical Genetics Seminar, Faculté de Médecine, Aix-Marseille Université, France
- 2021 Shaping Life 2 Meeting, Société Française de Biologie du Développement, France
- 2019 17th French Society for Myology Annual Meeting, Marseille, France
- 2012 12th International conference on limb development and regeneration, Montreal, Canada
- 2012 Midwest Society for Developmental Biology 50th conference, Cincinnati, USA
- 2012 EMBO workshop: Mesoscopic origins of cell behaviors during tissue morphogenesis, Corsica, France
Posters
- 2019 Society for Muscle Biology Annual Meeting, Costa Rica
- 2016 Shaping Life Meeting, Société Française de Biologie du Développement, France
- 2012 Jacque Monod Conference: evolution and emergence of developmental patterns, France
- 2012 Gordon Research Conference: Photosensory Receptors & Signal Transduction, USA
- 2011 Society for Developmental Biology 70th annual meeting, USA
- 2011 Gordon Research Conference: Cell Contact & Adhesion, USA
- 2010 9th International Conference on Zebrafish Development and Genetics, USA
- 2009 Society for Developmental Biology 68th annual meeting, USA
Honors and Awards
- 2019 Best Oral Presentation, 17th French Society for Myology Annual Meeting
- 2016 Best Poster, Shaping Life Meeting, Société Française de Biologie du Développement
- 2014 Best PhD Thesis in the general field of Developmental Biology, University of Chicago
- 2012 1st Place Oral Presentation, Midwest Society for Developmental Biology 50th conference
- 2012 Outstanding Student Talk, 12th International Conference on Limb Development and Regeneration
- 2012 Doolittle-Harrison Fellowship, University of Chicago
- 2011-2013 Chicago Biomedical Consortium Scholarship
- 2011 Woman’s Board Travel Award, University of Chicago
- 2011 Finalist, Best Student Poster Competition, Society for Developmental Biology 70th Conference
- 2006 Excellent Graduate Award, Peking University
- 2003-2006 Presidential Scholarship for Undergraduate Research, Peking University
- 2003-2006 Baosteel Education Foundation Scholarship